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Improving γ-retrovirus and lentivirus gene therapy vectors

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Detalhes bibliográficos
Resumo:"In the last decade gene therapy became an effective form of treatment for several disease indications. Successful clinical trials saved the lives of many patients otherwise with untreatable diseases and numerous products were granted market approval. Gammaretroviral and lentiviral vectors (γ- RV and LV) are the gene delivery vehicles with higher representation in clinical trials and commercialized virus-based products. (...)"
Autores principais:Oliveira, Ana
Assunto:gene therapy products biotechnological clinical applications vector design
Ano:2020
País:Portugal
Tipo de documento:tese de doutoramento
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:"In the last decade gene therapy became an effective form of treatment for several disease indications. Successful clinical trials saved the lives of many patients otherwise with untreatable diseases and numerous products were granted market approval. Gammaretroviral and lentiviral vectors (γ- RV and LV) are the gene delivery vehicles with higher representation in clinical trials and commercialized virus-based products. (...)"