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Improving γ-retrovirus and lentivirus gene therapy vectors

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Bibliographic Details
Summary:"In the last decade gene therapy became an effective form of treatment for several disease indications. Successful clinical trials saved the lives of many patients otherwise with untreatable diseases and numerous products were granted market approval. Gammaretroviral and lentiviral vectors (γ- RV and LV) are the gene delivery vehicles with higher representation in clinical trials and commercialized virus-based products. (...)"
Main Authors:Oliveira, Ana
Subject:gene therapy products biotechnological clinical applications vector design
Year:2020
Country:Portugal
Document type:doctoral thesis
Access type:open access
Associated institution:Universidade Nova de Lisboa
Language:English
Origin:Repositório Institucional da UNL
Description
Summary:"In the last decade gene therapy became an effective form of treatment for several disease indications. Successful clinical trials saved the lives of many patients otherwise with untreatable diseases and numerous products were granted market approval. Gammaretroviral and lentiviral vectors (γ- RV and LV) are the gene delivery vehicles with higher representation in clinical trials and commercialized virus-based products. (...)"