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Cell-based and cell-free strategies for cardiac repair

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Detalhes bibliográficos
Resumo:"Extensive work has been developed in the field of regenerative medicine towards addressing the fundamental mechanisms of loss of cardiac and vascular function in cardiovascular disease (CVD), particularly in heart failure. Therapies may tackle different phases and molecular processes over the course of post-insult cardiac tissue healing, either by modulating pathological responses and boosting endogenous repair pathways or by directly replacing injured areas with contractile macro tissues. (...)"
Autores principais:Louro, Ana
Assunto:stem cell cardiac repair
Ano:2022
País:Portugal
Tipo de documento:tese de doutoramento
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:"Extensive work has been developed in the field of regenerative medicine towards addressing the fundamental mechanisms of loss of cardiac and vascular function in cardiovascular disease (CVD), particularly in heart failure. Therapies may tackle different phases and molecular processes over the course of post-insult cardiac tissue healing, either by modulating pathological responses and boosting endogenous repair pathways or by directly replacing injured areas with contractile macro tissues. (...)"