Detalhes bibliográficos
| Resumo: | Bioactive compounds present in plant-based foods, and their metabolites derived from gut microbiota and endogenous metabolism, represent thousands of chemical structures of potential interest for human nutrition and health. State-of-the-art analytical methodologies, including untargeted metabolomics based on high-resolution mass spectrometry, are required for the profiling of these compounds in complex matrices, including plant food materials and biofluids. The aim of this project was to compare the analytical coverage of untargeted metabolomics methods independently developed and employed in various European platforms. In total, 56 chemical standards representing the most common classes of bioactive compounds spread over a wide chemical space were selected and analyzed by the participating platforms (n = 13) using their preferred untargeted method. The results were used to define analytical criteria for a successful analysis of plant food bioactives. Furthermore, they will serve as a basis for an optimized consensus method. |
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| Autores principais: | Koistinen, Ville Mikael |
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| Outros Autores: | da Silva, Andreia Bento; Abrankó, László; Low, Dorrain; Villalba, Rocio Garcia; Barberán, Francisco Tomás; Landberg, Rikard; Savolainen, Otto; Alvarez-Acero, Inmaculada; de Pascual-Teresa, Sonia; Van Poucke, Christof; Almeida, Conceição; Petrásková, Lucie; Valentová, Kateřina; Durand, Stephanie; Wiczkowski, Wiesław; Szawara-Nowak, Dorota; González-Domínguez, Raúl; Llorach, Rafael; Andrés-Lacueva, Cristina; Aura, Anna Marja; Seppänen-Laakso, Tuulikki; Hanhineva, Kati; Manach, Claudine; Bronze, Maria Rosário |
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| Assunto: | Mass spectrometry Method development Phytochemicals Endocrinology, Diabetes and Metabolism Biochemistry Molecular Biology SDG 3 - Good Health and Well-being |
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| Ano: | 2018 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Universidade Nova de Lisboa |
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| Idioma: | inglês |
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| Origem: | Repositório Institucional da UNL |
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