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Crystallographic studies on membrane and cytoplasmic enzymes

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Detalhes bibliográficos
Resumo:Haloacid dehalogenase (HAD) superfamily (CL0137), includes a diverse range of enzymes that use an aspartate carboxylate as nucleophile (Aravind et al., 1998; Koonin and Tatusov, 1994). There are ~79000 sequences classified into this superfamily in Pfam database and even more sequences, 148000, classified as HAD-like in the UniProt database (as of 19th February 2013).(...)
Autores principais:Nogly, Przemyslaw
Ano:2013
País:Portugal
Tipo de documento:tese de doutoramento
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:Haloacid dehalogenase (HAD) superfamily (CL0137), includes a diverse range of enzymes that use an aspartate carboxylate as nucleophile (Aravind et al., 1998; Koonin and Tatusov, 1994). There are ~79000 sequences classified into this superfamily in Pfam database and even more sequences, 148000, classified as HAD-like in the UniProt database (as of 19th February 2013).(...)