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Sulfonated Silica Coated CoFe2O4 Magnetic Nanoparticles for the Synthesis of 3,4-Dihydropyrimidin-2(1H)-One and Octahydroquinazoline Derivatives

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Detalhes bibliográficos
Resumo:Sulfonated-silica-coated cobalt ferrite (CoFe2O4) magnetic nanoparticles (MNPs-SiCoFe-SO3H) are efficient heterogeneous catalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-one and octahydroquinazoline derivatives in the absence of solvent. The effects of solvent, temperature, and catalyst amount on the reaction are investigated. The easy separation, reusability of the catalyst, simplicity of the procedure, mild reaction conditions, and good yields (68–95%) within short reaction times (15–70 min) are the advantages of this method. The catalyst can be reused up to eight times with not much loss of activity. Scanning electron microscopy images, X-ray diffraction spectra, and elemental analysis of the recycled catalyst show that the catalyst is stable after the reaction.
Autores principais:Afshari, Mozhgan
Outros Autores:Carabineiro, Sónia A. C.; Gorjizadeh, Maryam
Assunto:3,4-dihydropyrimidin-2(1H)-one derivative cobalt ferrite magnetic nanoparticles octahydroquinazoline derivatives sulfonic acid Catalysis General Environmental Science Physical and Theoretical Chemistry
Ano:2023
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:Sulfonated-silica-coated cobalt ferrite (CoFe2O4) magnetic nanoparticles (MNPs-SiCoFe-SO3H) are efficient heterogeneous catalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-one and octahydroquinazoline derivatives in the absence of solvent. The effects of solvent, temperature, and catalyst amount on the reaction are investigated. The easy separation, reusability of the catalyst, simplicity of the procedure, mild reaction conditions, and good yields (68–95%) within short reaction times (15–70 min) are the advantages of this method. The catalyst can be reused up to eight times with not much loss of activity. Scanning electron microscopy images, X-ray diffraction spectra, and elemental analysis of the recycled catalyst show that the catalyst is stable after the reaction.