Publicação

Synthesis of new enzyme stabilisers inspired by compatible solutes of hyperthermophilic microorganisms

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Detalhes bibliográficos
Resumo:In response to osmotic or heat stress, marine hyperthermophiles (thriving optimally at or above 80ºC) accumulate ionic compatible solutes such as α-Dmannosyl- D-glycerate (MG). It has been proposed that these hypersolutes stabilise intracellular components, such as proteins and enzymes, allowing them to withstand high growth temperatures.(...)
Autores principais:Lourenço, Eva Correia
Ano:2013
País:Portugal
Tipo de documento:tese de doutoramento
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:In response to osmotic or heat stress, marine hyperthermophiles (thriving optimally at or above 80ºC) accumulate ionic compatible solutes such as α-Dmannosyl- D-glycerate (MG). It has been proposed that these hypersolutes stabilise intracellular components, such as proteins and enzymes, allowing them to withstand high growth temperatures.(...)