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Deciphering the roles of ribonuclease PNPase in the human pathogen Listeria monocytogenes:

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Resumo:"PNPase is a 3’-5’ exoribonuclease that catalyses the degradation and processing of RNA. Although PNPase has been associated to virulence-related processes in bacteria, the regulatory networks under control of PNPase that contribute to virulence remain mostly elusive. Here, we studied the function of PNPase in the Gram-positive pathogenic bacterium Listeria monocytogenes, the infectious agent responsible for listeriosis, a foodborne infection associated with high morbidity and mortality in humans. L. monocytogenes is a facultative intracellular microorganism that thrives in a wide range of environmental conditions and endures different external stresses. Moreover, L. monocytogenes can adhere and form biofilms in several types of surfaces, namely in food-processing environments, making this bacterium a major burden for the food industry.(...)"
Autores principais:Quendera, Ana Patrícia
Assunto:Bacteria ranscriptomic studies bacterial pathogenicity
Ano:2023
País:Portugal
Tipo de documento:tese de doutoramento
Tipo de acesso:acesso embargado
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL

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