Publicação
Corrigendum to “Neurotoxic effects of MPTP on mouse cerebral cortex: Modulation of neuroinflammation as a neuroprotective strategy” [Mol. Cell. Neurosci., Volume 96, April 2019, Pages 1–9.](S1044743118303907)(10.1016/j.mcn.2019.01.003)
| Resumo: | The authors regret that in the original article there is an error in Fig. 5. Panel 5E incorrectly shows a blot for β-Actin that does not match the p-CREB blot shown above it. Nevertheless, this error does not affect the data presented in the original histogram, since quantifications of p-CREB and β-Actin were performed in the appropriate blots, corresponding to at least three independent experiments. Therefore, the histogram, image of the blot incubated with anti-p-CREB, and Figure legend are maintained. A corrected version of Fig. 5E is presented below. The authors state that this error does not change the scientific conclusions of the article in any way. [Figure presented] The authors would also like to clarify the readers that since the same gel/ membrane was used to probe for different proteins, they all share the same β-Actin blot as a loading control. This is the case of Figs. 1B, 2B, 3B and 4D (long-term treatments), Figs. 2A and 3A (short term treatments), and Fig. 5A and D (BV2 cells), where the correspondent β-Actin was used as a loading control in the detection of different proteins expression levels. The authors would like to apologize for any inconvenience caused. |
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| Autores principais: | Mendes, Mariana Oliveira |
| Outros Autores: | Rosa, Alexandra Isabel; Carvalho, Andreia Neves; Nunes, Maria João; Dionísio, Pedro; Rodrigues, Elsa; Costa, Daniela; Duarte-Silva, Sara; Maciel, Patrícia; Rodrigues, Cecília Maria Pereira; Gama, Maria João; Castro-Caldas, Margarida |
| Assunto: | Molecular Biology Cellular and Molecular Neuroscience Cell Biology |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | outro |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Nova de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório Institucional da UNL |
| Resumo: | The authors regret that in the original article there is an error in Fig. 5. Panel 5E incorrectly shows a blot for β-Actin that does not match the p-CREB blot shown above it. Nevertheless, this error does not affect the data presented in the original histogram, since quantifications of p-CREB and β-Actin were performed in the appropriate blots, corresponding to at least three independent experiments. Therefore, the histogram, image of the blot incubated with anti-p-CREB, and Figure legend are maintained. A corrected version of Fig. 5E is presented below. The authors state that this error does not change the scientific conclusions of the article in any way. [Figure presented] The authors would also like to clarify the readers that since the same gel/ membrane was used to probe for different proteins, they all share the same β-Actin blot as a loading control. This is the case of Figs. 1B, 2B, 3B and 4D (long-term treatments), Figs. 2A and 3A (short term treatments), and Fig. 5A and D (BV2 cells), where the correspondent β-Actin was used as a loading control in the detection of different proteins expression levels. The authors would like to apologize for any inconvenience caused. |
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