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Impedance Sensing Device for Wound Monitoring

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Resumo:A wound develops when a specific area of the body is exposed to prolonged pressure/cutting. In order to analyze the condition of the wound, it is necessary to take into account various parameters such as pH and humidity. The research work presented in this dissertation focuses on the study and optimization of an im- pedance device for measuring wound status. To fabricate this device, the laser irradiation technique was used, which consists of Laser Induced Graphene (LIG), a highly attractive material for creating and standardizing graphitic structures and electrodes specifically designed for use in electrochemical bio- sensors. Electrochemical Impedance Spectroscopy (EIS) was use to analyse the pH and humidity, providing a concise analysis of the control values for future application to the wound. During this project, efforts were made to develop a device capable of measuring variations in pH and humidity, so it was necessary to construct an electrode array capable of measuring all these varia- tions. After analysing the device, Raman peaks were identified with I2D/IG and ID/IG peak ratios of 0.59 and 1.18, respectively, showing low defect densities of LIG chemical structures and sheet resistances as low as 30.01 Ω. sq−1. After ensuring that the entire graphitisation process had been carried out successfully, impedance measurements were taken at pHs 3.5, 4.5, 6, 7.5 and 8.5, as well as humidity measurements over time, which allowed us to identify alterations around the electrodes and in view of these alterations could be suitable for future use on wounds.
Autores principais:Cabral, Ricardo Jorge Lima
Assunto:Wound Skin Electrochemical Impedance Spectroscopy Laser Induced Graphene
Ano:2023
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso aberto
Instituição associada:Universidade Nova de Lisboa
Idioma:inglês
Origem:Repositório Institucional da UNL
Descrição
Resumo:A wound develops when a specific area of the body is exposed to prolonged pressure/cutting. In order to analyze the condition of the wound, it is necessary to take into account various parameters such as pH and humidity. The research work presented in this dissertation focuses on the study and optimization of an im- pedance device for measuring wound status. To fabricate this device, the laser irradiation technique was used, which consists of Laser Induced Graphene (LIG), a highly attractive material for creating and standardizing graphitic structures and electrodes specifically designed for use in electrochemical bio- sensors. Electrochemical Impedance Spectroscopy (EIS) was use to analyse the pH and humidity, providing a concise analysis of the control values for future application to the wound. During this project, efforts were made to develop a device capable of measuring variations in pH and humidity, so it was necessary to construct an electrode array capable of measuring all these varia- tions. After analysing the device, Raman peaks were identified with I2D/IG and ID/IG peak ratios of 0.59 and 1.18, respectively, showing low defect densities of LIG chemical structures and sheet resistances as low as 30.01 Ω. sq−1. After ensuring that the entire graphitisation process had been carried out successfully, impedance measurements were taken at pHs 3.5, 4.5, 6, 7.5 and 8.5, as well as humidity measurements over time, which allowed us to identify alterations around the electrodes and in view of these alterations could be suitable for future use on wounds.