Publicação
Toker Cell Hyperplasia: a case report
| Resumo: | Abstract Toker cells are epithelial cells of the nipple epidermis, with a prevalence of about 10% of nipple sections stained with hematoxylin and eosin (H&E). More rarely, these cells are found in increased number, phenomenon known by Toker cell hyperplasia (TCH). TCH is a benign condition not associated with clinical manifestations. Reports regarding TCH refer to it as an incidental finding in skin biopsies, associated with other diseases, particularly, Paget’s Disease (PD). We report a case confirmed of TCH in a nipple associated with a non-specific chronic inflammatory lesion, with at least 17-year evolution. We emphasize the importance of biopsy to obtain a definitive diagnosis. |
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| Autores principais: | Ramos,Rui |
| Outros Autores: | Campelos,Sofia; Fonseca-Moutinho,José |
| Assunto: | Nipple Clear cells Hyperplasia Incidental findings Differential diagnosis |
| Ano: | 2021 |
| País: | Portugal |
| Tipo de documento: | relatório |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| Resumo: | Abstract Toker cells are epithelial cells of the nipple epidermis, with a prevalence of about 10% of nipple sections stained with hematoxylin and eosin (H&E). More rarely, these cells are found in increased number, phenomenon known by Toker cell hyperplasia (TCH). TCH is a benign condition not associated with clinical manifestations. Reports regarding TCH refer to it as an incidental finding in skin biopsies, associated with other diseases, particularly, Paget’s Disease (PD). We report a case confirmed of TCH in a nipple associated with a non-specific chronic inflammatory lesion, with at least 17-year evolution. We emphasize the importance of biopsy to obtain a definitive diagnosis. |
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