Publicação
What is new about HPV and pregnancy? The top articles of the past year
| Resumo: | Abstract Recent evidence indicates that the persistence of HPV infection is favored by the hormonal changes inherent to pregnancy, either through direct action on the viral genome or by promoting uncontrolled cellular proliferation, and it tends to resolve spontaneously in the postpartum period. Most cervical intraepithelial lesions remain stable or regress during pregnancy, with higher postpartum regression rates observed for lesions diagnosed during gestation. The pathophysiological mechanism underlying the association between HPV infection and preterm birth remains unclear. HPV-16 has been implicated as a high-risk genotype for preterm birth and vertical transmission and viral load may serve as a risk marker for these outcomes. |
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| Autores principais: | Urzal,Cecilia |
| Outros Autores: | Pedro,Amélia |
| Assunto: | Human papillomavirus Cervical intraepithelial lesions Pregnancy |
| Ano: | 2025 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| Resumo: | Abstract Recent evidence indicates that the persistence of HPV infection is favored by the hormonal changes inherent to pregnancy, either through direct action on the viral genome or by promoting uncontrolled cellular proliferation, and it tends to resolve spontaneously in the postpartum period. Most cervical intraepithelial lesions remain stable or regress during pregnancy, with higher postpartum regression rates observed for lesions diagnosed during gestation. The pathophysiological mechanism underlying the association between HPV infection and preterm birth remains unclear. HPV-16 has been implicated as a high-risk genotype for preterm birth and vertical transmission and viral load may serve as a risk marker for these outcomes. |
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