Publicação
Gadolinium Hypersensitivity: Review of Four Cases
| Resumo: | Abstract Immediate hypersensitivity reactions to gadolinium-based contrast agents are uncommon but can be life-threatening. We describe four cases of immediate hypersensitivity reactions to gadobutrol, including anaphylaxis. All patients underwent allergy work-up, with positive skin prick tests to gadobutrol. Two patients also demonstrated cross-reactivity to gadoteric acid. Disodium gadoxetate was tolerated in all cases in magnetic resonance. These findings highlight the importance of individualized allergy work-up to guide safe future imaging. |
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| Autores principais: | Gomes,Margarida |
| Outros Autores: | Ferreira,Sofia Cosme; Bernardino,Ana; Figueiredo,Pedro Samuel; Silva,Maria Inês; Duarte,Fátima Cabral |
| Assunto: | Gadolinium Drug hypersensitivity Anaphylaxis. |
| Ano: | 2026 |
| País: | Portugal |
| Tipo de documento: | relatório |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| Resumo: | Abstract Immediate hypersensitivity reactions to gadolinium-based contrast agents are uncommon but can be life-threatening. We describe four cases of immediate hypersensitivity reactions to gadobutrol, including anaphylaxis. All patients underwent allergy work-up, with positive skin prick tests to gadobutrol. Two patients also demonstrated cross-reactivity to gadoteric acid. Disodium gadoxetate was tolerated in all cases in magnetic resonance. These findings highlight the importance of individualized allergy work-up to guide safe future imaging. |
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