Detalhes bibliográficos
| Resumo: | Introduction: Lymphoproliferative disorders, particularly non-Hodgkins and Hodgkins lymphomas, are rare in patients with inflammatory bowel diseases. The use of thiopurines and infection by Epstein-Barr virus are well-known cofactors that can raise its prevalence. Other risk factors such as disease activity and biological treatment are the subject of discussion, without enough data in the literature to confirm a potential association. Methods: We report a case of Hodgkins lymphoma in a patient who had been treated with azathioprine and was on long-term monotherapy with infliximab. Conclusions: We stress the importance of recognizing the possible occurrence of a lymphoproliferative disorder in association with anti-tumor necrosis factor-α therapy. |
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| Autores principais: | Carvalho,Diana |
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| Outros Autores: | Russo,Pedro; Bernardes,Carlos; Saiote,Joana; Ramos,Gonçalo; Mascarenhas,Luis; Borges,Nuno; Ramos,Jaime |
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| Assunto: | Crohns disease Hodgkins disease chemically induced Infliximab Lymphoproliferative disorders Tumor necrosis factor-α |
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| Ano: | 2017 |
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| País: | Portugal |
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| Tipo de documento: | relatório |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Fundação para a Ciência e Tecnologia |
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| Idioma: | inglês |
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| Origem: | SciELO Portugal |
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