Publicação

Multiple Myeloma Involvement of the Pancreas: A Case Report of Pancreatic Extramedullary Plasmacytomas Causing Obstructive Jaundice

Ver documento

Detalhes bibliográficos
Resumo:Abstract Extramedullary plasmacytomas are rare tumors that can occur either as primary lesions or as a manifestation of multiple myeloma. Pancreatic involvement by plasma cell myeloma is very rare, accounting for less than 0.1% of pancreatic masses. Radiological findings are not specific. The most typical finding of pancreatic plasmacytoma on computed tomography has been reported as the presence of a focal multilobulated mass with homogeneous contrast enhancement. This is a case report of a 74-year-old woman with a previous history of stage III multiple myeloma presented to the emergency department with complaints of abdominal discomfort and painless jaundice. An abdominal ultrasound and computed tomography were performed and revealed a large mass in the topography of the pancreatic head. This mass caused dilatation of the intrahepatic bile ducts and the main bile duct. Subsequently, the patient underwent ultrasound-guided core biopsy of the pancreatic lesion, and the histological analysis of the specimen confirmed the diagnosis of pancreatic plasmacytoma. The purpose of this article is to present a very rare case of pancreatic extramedullary plasmacytomas, describe its epidemiology and clinical features, as well as illustrate its imaging findings.
Autores principais:Oliveira,Tiago
Outros Autores:Mendes,Vasco Ferrão; Antunes,Célia; Oliveira,Carlos; Oliveira,Rui Caetano; Donato,Paulo
Assunto:Pancreatic extramedullary plasmacytoma Multiple myeloma Pancreas Obstructive jaundice.
Ano:2022
País:Portugal
Tipo de documento:relatório
Tipo de acesso:acesso aberto
Instituição associada:Fundação para a Ciência e Tecnologia
Idioma:inglês
Origem:SciELO Portugal
Descrição
Resumo:Abstract Extramedullary plasmacytomas are rare tumors that can occur either as primary lesions or as a manifestation of multiple myeloma. Pancreatic involvement by plasma cell myeloma is very rare, accounting for less than 0.1% of pancreatic masses. Radiological findings are not specific. The most typical finding of pancreatic plasmacytoma on computed tomography has been reported as the presence of a focal multilobulated mass with homogeneous contrast enhancement. This is a case report of a 74-year-old woman with a previous history of stage III multiple myeloma presented to the emergency department with complaints of abdominal discomfort and painless jaundice. An abdominal ultrasound and computed tomography were performed and revealed a large mass in the topography of the pancreatic head. This mass caused dilatation of the intrahepatic bile ducts and the main bile duct. Subsequently, the patient underwent ultrasound-guided core biopsy of the pancreatic lesion, and the histological analysis of the specimen confirmed the diagnosis of pancreatic plasmacytoma. The purpose of this article is to present a very rare case of pancreatic extramedullary plasmacytomas, describe its epidemiology and clinical features, as well as illustrate its imaging findings.