Publicação
Pregnancy after intracytoplasmic sperm injection in couples with Kartagener syndrome
| Resumo: | Abstract Primary ciliary dyskinesia PCD is characterized by congenital impairment of mucociliary clearance. Kartagener syndrome KS is a rare subtype of PCD defined by the triad: bronchiectasis, chronic sinusitis and situs inversus. Male patients with KS have almost no spontaneous pregnancies due to complete immotility of their spermatozoa. Intracytoplasmic sperm injection ICSI is considered the treatment of choice despite showing lower fertilization rates in these patients. Different tests for assortment and selection of viable immotile spermatozoa are described. We present two cases of KS where pregnancy was achieved with ICSI using different methods of spermatozoa selection. |
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| Autores principais: | Miranda,Cláudia |
| Outros Autores: | Costa,Sofia; Coelho,Diana; Dantas,Sofia |
| Assunto: | Reproductive techniques, Assisted Kartagener syndrome Sperm injections, Intracytoplasmic Ciliary motility disorders Asthenozoospermia |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | relatório |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| Resumo: | Abstract Primary ciliary dyskinesia PCD is characterized by congenital impairment of mucociliary clearance. Kartagener syndrome KS is a rare subtype of PCD defined by the triad: bronchiectasis, chronic sinusitis and situs inversus. Male patients with KS have almost no spontaneous pregnancies due to complete immotility of their spermatozoa. Intracytoplasmic sperm injection ICSI is considered the treatment of choice despite showing lower fertilization rates in these patients. Different tests for assortment and selection of viable immotile spermatozoa are described. We present two cases of KS where pregnancy was achieved with ICSI using different methods of spermatozoa selection. |
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