Publicação
Solitary Fibrous Tumor of the Breast: A Rare Case
| Resumo: | Abstract A solitary fibrous tumor (SFT) is a rare neoplasm often found in the pleura. Breast SFT is extremely rare, with just a few cases reported in the literature. The 49-year-old woman presented with a palpable lump in right breast. Mammography revealed an oval circumscribed mass which on ultrasound corresponded to a well-defined hypoechoic nodule. The imaging findings are not pathognomonic, therefore definitive diagnosis requires histological examination and immune-histochemical analysis. Histologically, neoplastic cells may adopt spindle to ovoid morphology, and the growth pattern is variable. In the immune-histochemical study, the tumor cells are characterized by strong and diffuse positivity for CD34 and STAT-6. In conclusion, breast SFT is rare. Histology may show overlapping characteristics with other conditions, with STAT-6 being a sensitive and specific marker that makes the definitive diagnosis. Surgical resection is the gold standard treatment. Although most have a benign and indolent clinical course, long-term follow-up is recommended. |
|---|---|
| Autores principais: | Teixeira,Sofia |
| Outros Autores: | Flor-de-Lima,Beatriz; Cardoso,António; Madureira,António |
| Assunto: | Breast Solitary fibrous tumor Benign tumor. |
| Ano: | 2022 |
| País: | Portugal |
| Tipo de documento: | relatório |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| _version_ | 1868441944587239424 |
|---|---|
| author | Teixeira,Sofia |
| author2 | Flor-de-Lima,Beatriz Cardoso,António Madureira,António |
| author2_role | author author author |
| author_facet | Teixeira,Sofia Flor-de-Lima,Beatriz Cardoso,António Madureira,António |
| author_role | author |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Teixeira,Sofia\"},{\"Person.name\":\"Flor-de-Lima,Beatriz\"},{\"Person.name\":\"Cardoso,António\"},{\"Person.name\":\"Madureira,António\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Teixeira,Sofia Flor-de-Lima,Beatriz Cardoso,António Madureira,António |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Breast Solitary fibrous tumor Benign tumor. |
| datacite.titles.title.fl_str_mv | Solitary Fibrous Tumor of the Breast: A Rare Case |
| dc.creator.none.fl_str_mv | Teixeira,Sofia Flor-de-Lima,Beatriz Cardoso,António Madureira,António |
| dc.format.none.fl_str_mv | text/html |
| dc.identifier.none.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000100029 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Sociedade Portuguesa de Radiologia e Medicina Nuclear |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Acta Radiológica Portuguesa v.34 n.1 2022 |
| dc.subject.none.fl_str_mv | Breast Solitary fibrous tumor Benign tumor. |
| dc.title.fl_str_mv | Solitary Fibrous Tumor of the Breast: A Rare Case |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_93fc |
| description | Abstract A solitary fibrous tumor (SFT) is a rare neoplasm often found in the pleura. Breast SFT is extremely rare, with just a few cases reported in the literature. The 49-year-old woman presented with a palpable lump in right breast. Mammography revealed an oval circumscribed mass which on ultrasound corresponded to a well-defined hypoechoic nodule. The imaging findings are not pathognomonic, therefore definitive diagnosis requires histological examination and immune-histochemical analysis. Histologically, neoplastic cells may adopt spindle to ovoid morphology, and the growth pattern is variable. In the immune-histochemical study, the tumor cells are characterized by strong and diffuse positivity for CD34 and STAT-6. In conclusion, breast SFT is rare. Histology may show overlapping characteristics with other conditions, with STAT-6 being a sensitive and specific marker that makes the definitive diagnosis. Surgical resection is the gold standard treatment. Although most have a benign and indolent clinical course, long-term follow-up is recommended. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | report |
| id | scielopt_8a0cc36728f7f5d15f67654ecddd0c49 |
| identifier.url.fl_str_mv | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000100029 |
| instacron_str | SciELO |
| institution | Fundação para a Ciência e Tecnologia |
| instname_str | Fundação para a Ciência e Tecnologia |
| language | eng |
| network_acronym_str | scielopt |
| network_name_str | SciELO Portugal |
| oai_identifier_str | oai:scielo:S2183-13512022000100029 |
| organization_str_mv | urn:organizationAcronym:scielo |
| person_str_mv | Teixeira,Sofia Flor-de-Lima,Beatriz Cardoso,António Madureira,António |
| publishDate | 2022 |
| publisher.none.fl_str_mv | Sociedade Portuguesa de Radiologia e Medicina Nuclear |
| reponame_str | SciELO Portugal |
| repository_id_str | urn:repositoryAcronym:scielopt |
| service_str_mv | urn:repositoryAcronym:scielopt |
| spelling | Solitary Fibrous Tumor of the Breast: A Rare CaseTeixeira,SofiaFlor-de-Lima,BeatrizCardoso,AntónioMadureira,AntónioBreastSolitary fibrous tumorBenign tumor.open accesshttp://purl.org/coar/access_right/c_abf2http://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000100029URLhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000100029URLHasVersion2022-04-01Abstract A solitary fibrous tumor (SFT) is a rare neoplasm often found in the pleura. Breast SFT is extremely rare, with just a few cases reported in the literature. The 49-year-old woman presented with a palpable lump in right breast. Mammography revealed an oval circumscribed mass which on ultrasound corresponded to a well-defined hypoechoic nodule. The imaging findings are not pathognomonic, therefore definitive diagnosis requires histological examination and immune-histochemical analysis. Histologically, neoplastic cells may adopt spindle to ovoid morphology, and the growth pattern is variable. In the immune-histochemical study, the tumor cells are characterized by strong and diffuse positivity for CD34 and STAT-6. In conclusion, breast SFT is rare. Histology may show overlapping characteristics with other conditions, with STAT-6 being a sensitive and specific marker that makes the definitive diagnosis. Surgical resection is the gold standard treatment. Although most have a benign and indolent clinical course, long-term follow-up is recommended.Sociedade Portuguesa de Radiologia e Medicina NuclearActa Radiológica Portuguesa v.34 n.1 2022text/htmlengreporthttp://purl.org/coar/resource_type/c_93fcother research product |
| spellingShingle | Solitary Fibrous Tumor of the Breast: A Rare Case Teixeira,Sofia Breast Solitary fibrous tumor Benign tumor. |
| status | SINGLETON |
| subject.fl_str_mv | Breast Solitary fibrous tumor Benign tumor. |
| title | Solitary Fibrous Tumor of the Breast: A Rare Case |
| title_full | Solitary Fibrous Tumor of the Breast: A Rare Case |
| title_fullStr | Solitary Fibrous Tumor of the Breast: A Rare Case |
| title_full_unstemmed | Solitary Fibrous Tumor of the Breast: A Rare Case |
| title_short | Solitary Fibrous Tumor of the Breast: A Rare Case |
| title_sort | Solitary Fibrous Tumor of the Breast: A Rare Case |
| topic | Breast Solitary fibrous tumor Benign tumor. |
| topic_facet | Breast Solitary fibrous tumor Benign tumor. |
| url | http://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000100029 |
| visible | 1 |