Detalhes bibliográficos
| Resumo: | Abstract Carriers of the mutated CDH1 gene have an increased risk of developing early-onset signet-ring cell (diffuse) gastric cancer. We present a case of a young patient with a confirmed mutation of the CDH1 gene, who was diagnosed with a gastric marginal zone B-cell lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT lymphoma) from surveillance endoscopy. He underwent Helicobacter pylori eradication treatment and was subsequently submitted to a total prophylactic gastrectomy. The surgical specimen only revealed foci of signet-ring cell carcinoma (SRCC) in situ without lymphoma signs. We highlight here the occurrence of other pathology in high-risk patients as well as its possible influence on the decision to perform gastrectomy. |
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| Autores principais: | Pinto,Cláudia |
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| Outros Autores: | Cunha,Ana Luísa; Rodrigues,Ângelo; Dias,Renata; Brandão,Catarina; Dinis-Ribeiro,Mário |
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| Assunto: | CDH1 protein Stomach neoplasms Helicobacter pylori Marginal zone B-cell lymphoma |
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| Ano: | 2022 |
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| País: | Portugal |
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| Tipo de documento: | relatório |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Fundação para a Ciência e Tecnologia |
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| Idioma: | inglês |
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| Origem: | SciELO Portugal |
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