Publicação
Predictors of Inappropriate Proton Pump Inhibitor Prescription in an Internal Medicine Department
| Resumo: | Introduction:Proton pump inhibitors (PPIs) are used in the treatment of gastrointestinal pathology and prevention of upper gastrointestinal bleeding. They are frequently misused in hospitalized patients. Methods:We conducted an observational cross-sectional study between 15th March and 15th May 2015 to evaluate the prescription pattern of PPIs in an Internal Medicine ward regarding indications and costs. Results:Five hundred and eighty five admissions were included with an average age of 75 years. One hundred and sixty three cases were medicated with a PPI prior to admission, half of them without indication. Three hundred seventy-two cases were prescribed a PPI on admission/during hospital stay but only 63 cases had a proper indication meaning that 83% were inadequately medicated. Predictors of inadequate PPI prescription were female sex, age = 75 years and being medicated with a PPI prior to admission. Conclusion: Total costs, directly related to PPIs were set at 1079.96, on average 2.72 per episode. Therapy with PPIs should be reviewed to decrease inadequate prescriptions and costs. |
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| Autores principais: | Santos,Luís Ramos dos |
| Outros Autores: | Nóbrega,Sofia; Santos,Dina; Lélis,Manuela; Brazão,Maria da Luz |
| Assunto: | Hospital Departments Inappropriate Prescribing Internal Medicine Proton Pump Inhibitors/therapeutic uso |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Fundação para a Ciência e Tecnologia |
| Idioma: | inglês |
| Origem: | SciELO Portugal |
| Resumo: | Introduction:Proton pump inhibitors (PPIs) are used in the treatment of gastrointestinal pathology and prevention of upper gastrointestinal bleeding. They are frequently misused in hospitalized patients. Methods:We conducted an observational cross-sectional study between 15th March and 15th May 2015 to evaluate the prescription pattern of PPIs in an Internal Medicine ward regarding indications and costs. Results:Five hundred and eighty five admissions were included with an average age of 75 years. One hundred and sixty three cases were medicated with a PPI prior to admission, half of them without indication. Three hundred seventy-two cases were prescribed a PPI on admission/during hospital stay but only 63 cases had a proper indication meaning that 83% were inadequately medicated. Predictors of inadequate PPI prescription were female sex, age = 75 years and being medicated with a PPI prior to admission. Conclusion: Total costs, directly related to PPIs were set at 1079.96, on average 2.72 per episode. Therapy with PPIs should be reviewed to decrease inadequate prescriptions and costs. |
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