Publicação
Kaposi Sarcoma in Solid Organ Transplant Recipients: A challenging Case
| Resumo: | Kaposi sarcoma is a low-grade vascular tumor, associated with human herpesvirus-8 infection. Solid organ transplant recipients have a much higher risk of this malignancy, with estimated incidence rates increased 84 to 500 times. The risk is even higher in some ethnic groups, already with a higher incidence of this disease. We report a case of a 37-year-old African male, a kidney transplant recipient, with a Kaposi sarcoma refractory to different treatment options. The present case puts in evidence the challenges associated with the management of this disease in this high-risk population and highlights the role of a multidisciplinary approach to achieve effective treatment, particularly in advanced and refractory forms. |
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| Autores principais: | Macedo, Daniela |
| Outros Autores: | Garrido, Pedro Miguel; Fernandes, Isabel; Santana, Alice; Guerra, José; Borges-Costa, João |
| Assunto: | Immunocompromised Host Organ Transplantation/adverse effects Sarcoma, Kaposi/etiology Transplant Recipients Hospedeiro Imunocomprometido Sarcoma de Kaposi/etiologia Transplantados de Órgãos/ efeitos adversos |
| Ano: | 2019 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Instituição associada: | Sociedade Portuguesa de Dermatologia e Venereologia |
| Idioma: | inglês |
| Origem: | Portuguese Journal of Dermatology |
| Resumo: | Kaposi sarcoma is a low-grade vascular tumor, associated with human herpesvirus-8 infection. Solid organ transplant recipients have a much higher risk of this malignancy, with estimated incidence rates increased 84 to 500 times. The risk is even higher in some ethnic groups, already with a higher incidence of this disease. We report a case of a 37-year-old African male, a kidney transplant recipient, with a Kaposi sarcoma refractory to different treatment options. The present case puts in evidence the challenges associated with the management of this disease in this high-risk population and highlights the role of a multidisciplinary approach to achieve effective treatment, particularly in advanced and refractory forms. |
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