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Angiomatoid Spitz Nevus

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Detalhes bibliográficos
Resumo:Angiomatoid Spitz nevus is a rare tumor that combines the classic aspects of Spitz nevus with a prominent vascular component. Clinically, it presents as a pink or brownish papule, usually solitary, in the extremities of young adults. On histology, it is characterized by a proliferation of epithelioid or spindle cell melanocytes embedded in a fibrous stroma, where a dense proliferation of small vessels is evident. The differential diagnosis with malignant melanoma can be difficult, particularly with the desmoplastic variant or with those with marked regression. Its behavior is benign, as suggested by the absence of local recurrences or distant metastases during long-term follow-up.
Autores principais:Lopes, Jorge
Outros Autores:Afonso-João, David; Teixeira, Diogo; Baptista, Armando
Assunto:Nevus, Epithelioid and Spindle Cell Skin Neoplasms Neoplasias da Pele Nevo de Células Epitelioides e Fusiformes
Ano:2020
País:Portugal
Tipo de documento:artigo
Tipo de acesso:unknown
Instituição associada:Sociedade Portuguesa de Dermatologia e Venereologia
Idioma:inglês
Origem:Portuguese Journal of Dermatology
Descrição
Resumo:Angiomatoid Spitz nevus is a rare tumor that combines the classic aspects of Spitz nevus with a prominent vascular component. Clinically, it presents as a pink or brownish papule, usually solitary, in the extremities of young adults. On histology, it is characterized by a proliferation of epithelioid or spindle cell melanocytes embedded in a fibrous stroma, where a dense proliferation of small vessels is evident. The differential diagnosis with malignant melanoma can be difficult, particularly with the desmoplastic variant or with those with marked regression. Its behavior is benign, as suggested by the absence of local recurrences or distant metastases during long-term follow-up.