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Cutaneous Histoplasmosis in AIDS Patient: Case Report

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Resumo:This report describes a case of disseminated cutaneous histoplasmosis in a 30 years old black woman, born and living in Mozambique, with disseminated eruptive multiple papules, some of them with erosions, localized also in palms, plants and oropharyngeal mucosa. The HIV 2 test was positive and the CD4 count was 1 cel/mm3. Histopathology was compatible with infection by Histoplasma capsulatum. She was treated with amphotericin B during 21 days, with clinical improvement, followed by oral fluconazole 400 mg/day and antiretroviral, but she died 13 months later from gastroenteritis.
Autores principais:Kombo, A.
Outros Autores:Monteiro, I.; César, N.; Catorze, G.; Henriques, M.; Manuel, R.; Cunha, A.; Luciano, G.
Assunto:Acquired Immunodeficiency Syndrome AIDS-Related Opportunistic Infections Dermatomycoses Histoplasmosis Dermatomicoses Infecções Oportunistas Relacionadas com a SIDA Histoplasmose Síndrome da Imunodeficiência Adquirida
Ano:2018
País:Portugal
Tipo de documento:artigo
Instituição associada:Sociedade Portuguesa de Dermatologia e Venereologia
Idioma:português
Origem:Portuguese Journal of Dermatology
Descrição
Resumo:This report describes a case of disseminated cutaneous histoplasmosis in a 30 years old black woman, born and living in Mozambique, with disseminated eruptive multiple papules, some of them with erosions, localized also in palms, plants and oropharyngeal mucosa. The HIV 2 test was positive and the CD4 count was 1 cel/mm3. Histopathology was compatible with infection by Histoplasma capsulatum. She was treated with amphotericin B during 21 days, with clinical improvement, followed by oral fluconazole 400 mg/day and antiretroviral, but she died 13 months later from gastroenteritis.