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PSORIASIS TREATMENT IN PEDIATRIC AGE – PART I: TOPICAL TREATMENT

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Detalhes bibliográficos
Resumo:Psoriasis is a chronic inflammatory disorder, multisystem and immunologically mediated. Approximately one third of adults refer the age of onset before 16, representing about 4% of all dermatoses seen in pediatric age. The majority of cases are mild and adequately managed with topical medications. A minor subset of children present with severe, rapidly evolving disease that requires systemic therapy. The use of these therapies is limited by the risk of toxicity, the low acceptance and lack of studies to validate and guide the use of most of these drugs in children. This is the first of two articles which aim to review the topical (Part I) and systemic (Part II) treatment options available, as well as its safety and efficacy in children.
Autores principais:Cruz, Maria João
Outros Autores:Magina, Sofia; Baudrier, Teresa; Azevedo, Filomena
Assunto:Psoriasis Child Topics Treatment Psoríase Criança Tópicos Tratamento
Ano:2016
País:Portugal
Tipo de documento:artigo
Instituição associada:Sociedade Portuguesa de Dermatologia e Venereologia
Idioma:português
Origem:Portuguese Journal of Dermatology
Descrição
Resumo:Psoriasis is a chronic inflammatory disorder, multisystem and immunologically mediated. Approximately one third of adults refer the age of onset before 16, representing about 4% of all dermatoses seen in pediatric age. The majority of cases are mild and adequately managed with topical medications. A minor subset of children present with severe, rapidly evolving disease that requires systemic therapy. The use of these therapies is limited by the risk of toxicity, the low acceptance and lack of studies to validate and guide the use of most of these drugs in children. This is the first of two articles which aim to review the topical (Part I) and systemic (Part II) treatment options available, as well as its safety and efficacy in children.