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An Unexpected Cause of Tetraparesis – Clinical Case

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Resumo:The authors report a clinical case of an 83-year-old-woman who was attended the Emergency Service for decreased strength in her limbs. The physical examination presented tetraparesis, with muscle strength grade 1/5 in the lower limbs, grade 3/5 in the upper limbs and absent deep tendon reflexes. The lumbar puncture showed albuminocytologic dissociation. It was assumed a diagnosis of Guillain-Barre syndrome and immunoglobulins were started. Progressive clinical deterioration with respiratory failure and need of non-invasive ventilation have followed. Palpable abdominal mass, leading to an abdominal CT scan showed multiple nodules of peritoneal surfaces, large mass with 13 cm diameter and multiple enlarged lymph nodes. Biopsy of abdominal mass histology compatible with centroblastic variant of diffuse large B-cell lymphoma. Started corticosteroid therapy, with unfavorable clinical course, and the patient died. The authors report this case due to rare form the lymphoma was presented
Autores principais:Barbosa, Susana
Outros Autores:Pereira, Énio; Meireles Brandão, Lúcia; Felgueiras, Paula; Guerra, Diana; Pinto, Alfredo
Assunto:Debilidade Muscular Linforma não-Hodgkin Quadriplegia Síndrome de Guillain-Barré Guillain-Barre Syndrome Lymphoma, Non-Hodgkin Muscle Weakness Quadriplegia
Ano:2015
País:Portugal
Tipo de documento:artigo
Tipo de acesso:unknown
Instituição associada:Sociedade Portuguesa de Medicina Interna
Idioma:português
Origem:Revista Portuguesa de Medicina Interna
Descrição
Resumo:The authors report a clinical case of an 83-year-old-woman who was attended the Emergency Service for decreased strength in her limbs. The physical examination presented tetraparesis, with muscle strength grade 1/5 in the lower limbs, grade 3/5 in the upper limbs and absent deep tendon reflexes. The lumbar puncture showed albuminocytologic dissociation. It was assumed a diagnosis of Guillain-Barre syndrome and immunoglobulins were started. Progressive clinical deterioration with respiratory failure and need of non-invasive ventilation have followed. Palpable abdominal mass, leading to an abdominal CT scan showed multiple nodules of peritoneal surfaces, large mass with 13 cm diameter and multiple enlarged lymph nodes. Biopsy of abdominal mass histology compatible with centroblastic variant of diffuse large B-cell lymphoma. Started corticosteroid therapy, with unfavorable clinical course, and the patient died. The authors report this case due to rare form the lymphoma was presented