Publicação
Central Pain and Stroke: A Short Narrative Review
| Resumo: | Introduction: Pain can be a sequel of a stroke, and is often undervalued, limiting the patient´s quality of life. This study aimed to make a narrative review on central post stroke pain (CPSP) including its definition, prevalence, clinical presentation, diagnosis, pathophysiology, and treatment. Methods: A search was performed on PubMed© looking for articles in Portuguese or English, with full text, about human research, in adults, using the terms “central” and “pain” and “post stroke”. Thirty-three articles were included in this narrative review. Discussion: CPSP is a neuropathic pain syndrome resulting from an insult to the central nervous system. It is characterized by pain and sensory abnormalities, such as allodynia and hyperalgesia. Prevalence varies from 5% to 50% (thalamic stroke) and it is often underdiagnosed and undertreated. Treatment includes mainly antidepressants and anticonvulsants, and a non- -pharmacological approach. The surgical approach is intended for refractory cases. Conclusion: Management of CPSP is challenging and requires an individualized approach. Future studies may clarify CPSP´s pathophysiology, define clear diagnostic criteria, and collect evidence that allows a more effective treatment. |
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| Autores principais: | Reis-Pina, Paulo |
| Outros Autores: | Ramos, Maria Sofia |
| Assunto: | Acidente Vascular Cerebral Dor Neuropática Hiperalgesia Perceção da Dor Sensibilização do Sistema Nervoso Central Central Nervous System Sensitization Hyperalgesia Neuralgia Pain Perception Stroke |
| Ano: | 2021 |
| País: | portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | unknown |
| Instituição associada: | Sociedade Portuguesa de Medicina Interna |
| Idioma: | português |
| Origem: | Revista Portuguesa de Medicina Interna |
| Resumo: | Introduction: Pain can be a sequel of a stroke, and is often undervalued, limiting the patient´s quality of life. This study aimed to make a narrative review on central post stroke pain (CPSP) including its definition, prevalence, clinical presentation, diagnosis, pathophysiology, and treatment. Methods: A search was performed on PubMed© looking for articles in Portuguese or English, with full text, about human research, in adults, using the terms “central” and “pain” and “post stroke”. Thirty-three articles were included in this narrative review. Discussion: CPSP is a neuropathic pain syndrome resulting from an insult to the central nervous system. It is characterized by pain and sensory abnormalities, such as allodynia and hyperalgesia. Prevalence varies from 5% to 50% (thalamic stroke) and it is often underdiagnosed and undertreated. Treatment includes mainly antidepressants and anticonvulsants, and a non- -pharmacological approach. The surgical approach is intended for refractory cases. Conclusion: Management of CPSP is challenging and requires an individualized approach. Future studies may clarify CPSP´s pathophysiology, define clear diagnostic criteria, and collect evidence that allows a more effective treatment. |
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