Publicação
Anaemia of chronic diseases
| Resumo: | The authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed. |
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| Autores principais: | Sousa, Gabriela |
| Outros Autores: | Alfaiate, Teresa; Ferreira, Mário Rui; Carvalho, Teresa; Veiga e Moura, António |
| Assunto: | anemia doença crónica macrófagos interleuquinas patogenia eritropoietina Anaemia chronic disease macrophages interleukins pathogenesis erythropoietina |
| Ano: | 1999 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Instituição associada: | Sociedade Portuguesa de Medicina Interna |
| Idioma: | português |
| Origem: | Revista Portuguesa de Medicina Interna |
| Resumo: | The authors review and discuss the current concepts concerning anaemia which coexists with multiple chronic diseases, denominated "Anaemia of Chronic Diseases". This is the most common form of anaemia in hospitalised medical patients. lt se/dom requires treatment as it normally resolves once the underlying disease has been successfully controlled. The most important pathogenic mechanism is a block in the re-utilisation of haemoglobin iron. A mechanism, mediated by the release of interleukins and other infiammation mediators, in response to tissue damage. ln terms of differential diagnosis, the problem is to distinguish between "Anaemia of Chronic Diseases" and "Sideropenic Anaemia" as the appropriate treatment differs. The therapeutic role of erythropoietin is discussed. |
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