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Bacteriophage Phi 6 as surrogate and human-harmless viruses to study anti-SARS-CoV-2 approaches

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Detalhes bibliográficos
Resumo:Given safety challenges in conducting laboratory work with highly infectious human coronaviruses (pathogenicity, genetic mutations rate, biosafety level 3 and 4 requirements), many researchers have valued the potential of bacteriophages as appropriate viral surrogate to measure humans enveloped virus’ survival, transfer and removal. The use of phage Φ6 seems to be useful as coronavirus surrogate to assess the effectiveness of anti-SARS-CoV-2 approaches, providing important insights concerning COVID-19 pandemic and human public health.
Autores principais:Barros, Joana
Outros Autores:Monteiro, Fernando; Ferraz, Maria Pia
Assunto:SARS-CoV-2 COVID-19 Bacteriophage Φ6
Ano:2021
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade Fernando Pessoa
Idioma:inglês
Origem:Repositório Institucional - Universidade Fernando Pessoa
Descrição
Resumo:Given safety challenges in conducting laboratory work with highly infectious human coronaviruses (pathogenicity, genetic mutations rate, biosafety level 3 and 4 requirements), many researchers have valued the potential of bacteriophages as appropriate viral surrogate to measure humans enveloped virus’ survival, transfer and removal. The use of phage Φ6 seems to be useful as coronavirus surrogate to assess the effectiveness of anti-SARS-CoV-2 approaches, providing important insights concerning COVID-19 pandemic and human public health.