Publicação
Oral considerations in pediatric patients with acute lymphoblastic leukemia
| Resumo: | Introduction: Acute lymphocytic leukemia is one of the most common type of cancer in children and it is characterized by excessive and disordered immature leukocytes in the bone marrow. Objectives: Identify oral and general common signs and symptoms of Acute lymphocytic leukemia in pediatric patients and when receiving chemotherapy, hematopoietic cell transplantation, and/or radiation therapy. Methods: A systematic literature search in PubMed, Scielo and B-on data base was made, giving preference to articles from the last 10 years and with free access, using the following keywords: children, acute lymphoblastic leukemia, treatment, early effects, long-term effects, oral health. Development: There are many oral manifestations in this patients either from the disease it self or from the treatment. Some of the most common are: bone alterations, trismus, gingival bleeding, echymoses, mucosal pallor, mucositis, xerostomia and oportunistic infections. Discussion and Conclusion: The dental clinicians may contribute to a higher survival rate and improved oral related quality of life in ALL patients since they might enable an early diagnose, they are able to support antineoplastic treatment success and monitoring / treatment of long term changes. Dentists shall, therefore, be a critical element of the multidisciplinary team in hematology-oncology context. |
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| Autores principais: | Aroso, Ricardo |
| Assunto: | Children Acute lymphoblastic leukemia Treatment Early effects Long-term effects Oral health Crianças Leucemia linfocítica aguda Tratamento Efeitos a curto prazo Efeitos a longo prazo Saúde oral |
| Ano: | 2017 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Fernando Pessoa |
| Idioma: | inglês |
| Origem: | Repositório Institucional - Universidade Fernando Pessoa |
| Resumo: | Introduction: Acute lymphocytic leukemia is one of the most common type of cancer in children and it is characterized by excessive and disordered immature leukocytes in the bone marrow. Objectives: Identify oral and general common signs and symptoms of Acute lymphocytic leukemia in pediatric patients and when receiving chemotherapy, hematopoietic cell transplantation, and/or radiation therapy. Methods: A systematic literature search in PubMed, Scielo and B-on data base was made, giving preference to articles from the last 10 years and with free access, using the following keywords: children, acute lymphoblastic leukemia, treatment, early effects, long-term effects, oral health. Development: There are many oral manifestations in this patients either from the disease it self or from the treatment. Some of the most common are: bone alterations, trismus, gingival bleeding, echymoses, mucosal pallor, mucositis, xerostomia and oportunistic infections. Discussion and Conclusion: The dental clinicians may contribute to a higher survival rate and improved oral related quality of life in ALL patients since they might enable an early diagnose, they are able to support antineoplastic treatment success and monitoring / treatment of long term changes. Dentists shall, therefore, be a critical element of the multidisciplinary team in hematology-oncology context. |
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