Publicação
De-escalação da antibioterapia na sépsis grave e choque séptico numa unidade de cuidados intensivos : estudo epidemiológico no serviço de medicina intensiva do Hospital de Santa Maria
| Resumo: | Sepsis and associated syndromes are increasing in prevalence at developed countries where risk factors such as immunosuppression and advanced age with increasing number of co-morbidities are more and more frequent. Even though the number of cases are increasing, the survival rate has also been increasing. A various number of factors can determine the prognosis of patients, such as the de-escalation of antibiotherapy by various authors. De-escalation should be thought of not only as a benefit in direct mortality but also as a policy for cost reduction, decrease in internment time, and prevention against the large specter antibiotic resistant pathogens. This study aims to assess the possibility of de-escalation of antibiotherapy in an intensive care unit of the Hospital de Santa Maria. As general results, on a population of 30 patients with severe sepsis or septic shock we observed a de-escalation rate of 33.3%, which are usual in these types of intensive care units. |
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| Autores principais: | Reis, Rúben Miguel da Silva |
| Assunto: | Sépsis grave Choque séptico De-escalação Antibioterapia empírica Cuidados intensivos |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | português |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Sepsis and associated syndromes are increasing in prevalence at developed countries where risk factors such as immunosuppression and advanced age with increasing number of co-morbidities are more and more frequent. Even though the number of cases are increasing, the survival rate has also been increasing. A various number of factors can determine the prognosis of patients, such as the de-escalation of antibiotherapy by various authors. De-escalation should be thought of not only as a benefit in direct mortality but also as a policy for cost reduction, decrease in internment time, and prevention against the large specter antibiotic resistant pathogens. This study aims to assess the possibility of de-escalation of antibiotherapy in an intensive care unit of the Hospital de Santa Maria. As general results, on a population of 30 patients with severe sepsis or septic shock we observed a de-escalation rate of 33.3%, which are usual in these types of intensive care units. |
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