Detalhes bibliográficos
| Resumo: | A new chemoselective (enzymatic desymmetrization/Ru-catalyzed C−H activation) sequence to obtain differently substituted furans from the largely available 2,5-furandicarboxylic acid (FDCA) was developed. Series of di- and trisubstituted furans were prepared in very good yields and excellent chemoselectivity. This study discloses a new approach towards valorization of the furanics platform through the use of FDCA as a stable intermediate, thus circumventing the chemical instability of the parent 5-hydroxymethylfurfural. |
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| Autores principais: | Ravasco, João M. J. M. |
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| Outros Autores: | Monteiro, Carlos M.; Siopa, Filipa; Trindade, Alexandre Fonseca; Oble, Julie; Poli, Giovanni; Simeonov, Svilen; Afonso, Carlos |
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| Assunto: | biocatalysis biomass C-H activation continuous flow furanic platform |
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| Ano: | 2019 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso restrito |
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| Instituição associada: | Universidade de Lisboa |
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| Idioma: | inglês |
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| Origem: | Repositório da Universidade de Lisboa |
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