Publicação
Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53
| Resumo: | Drug resistance to 5-fluorouracil (5-FU) is still a major limitation to its clinical use. In addition, the clinical value of p53 as a predictive marker for 5-FU-based chemotherapy remains a matter of debate. Here, we used HCTI 16 human colorectal cancer c |
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| Autores principais: | Borralho, Pedro M. |
| Outros Autores: | da Silva, Isabel B. Moreira; Aranha, Marcia M.; Albuquerque, Cristina; Leitao, Carlos Nobre; Steer, Clifford J.; Rodrigues, Cecilia M. P. |
| Assunto: | Biochemistry & Molecular Biology Biophysics Cell Biology |
| Ano: | 2007 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso a metadados |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Drug resistance to 5-fluorouracil (5-FU) is still a major limitation to its clinical use. In addition, the clinical value of p53 as a predictive marker for 5-FU-based chemotherapy remains a matter of debate. Here, we used HCTI 16 human colorectal cancer c |
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