Publicação
Revisiting a series of epithelial salivary gland tumors in children and adolescents in southern Portugal
| Resumo: | Introduction: Salivary gland tumors in pediatric population are extremely rare. Most papers are case reports or small series of cases. Objective: To analyze the clinical, epidemiological and histopathological features and outcomes of epithelial salivary gland tumors occurring in the pediatric population. Methods: During a 50-year period, a total of 54 epithelial salivary gland tumors were diagnosed in patients less than 19 years at Instituto Português de Oncologia de Lisboa Francisco Gentil. Demographic, clinical and follow-up data were obtained from medical records and histopathological features were reviewed. Results: The mean of age of the patients was 13.4 years. One case was congenital and the male to female ratio was 1:1.1. Thirty-seven tumors (68.5%) were benign and 17 (31.5%) malignant. Pleomorphic adenoma was the most common tumor type (61.1%), followed by mucoepidermoid carcinoma (22.2%). The parotid gland was affected in most cases (77.8%), followed by minor glands involvement (14.8%). All tumors in submandibular gland were benign. The recurrence rate was 21.6% for benign tumors and the 5-year survival rate was 82.4% for malignant tumors. Conclusions: Epithelial salivary gland tumors in southern Portugal pediatric patients are rare, specialy malignant tumors. Parotid gland is the most common involved site and pleomorphic adenoma and mucoepidermoid carcinoma are the most common benign and malignant tumor, respectively. There is a slight female predominance. |
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| Autores principais: | Travessa, André Miguel Ramos |
| Assunto: | Pleomorphic adenoma Children Tumor Salivary gland Pediatric Epithelial |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Introduction: Salivary gland tumors in pediatric population are extremely rare. Most papers are case reports or small series of cases. Objective: To analyze the clinical, epidemiological and histopathological features and outcomes of epithelial salivary gland tumors occurring in the pediatric population. Methods: During a 50-year period, a total of 54 epithelial salivary gland tumors were diagnosed in patients less than 19 years at Instituto Português de Oncologia de Lisboa Francisco Gentil. Demographic, clinical and follow-up data were obtained from medical records and histopathological features were reviewed. Results: The mean of age of the patients was 13.4 years. One case was congenital and the male to female ratio was 1:1.1. Thirty-seven tumors (68.5%) were benign and 17 (31.5%) malignant. Pleomorphic adenoma was the most common tumor type (61.1%), followed by mucoepidermoid carcinoma (22.2%). The parotid gland was affected in most cases (77.8%), followed by minor glands involvement (14.8%). All tumors in submandibular gland were benign. The recurrence rate was 21.6% for benign tumors and the 5-year survival rate was 82.4% for malignant tumors. Conclusions: Epithelial salivary gland tumors in southern Portugal pediatric patients are rare, specialy malignant tumors. Parotid gland is the most common involved site and pleomorphic adenoma and mucoepidermoid carcinoma are the most common benign and malignant tumor, respectively. There is a slight female predominance. |
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