Publicação

A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance

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Detalhes bibliográficos
Resumo:Eukaryotes regulate the effective dosage of their ribosomal RNA (rRNA) genes, expressing fewer than half of the genes at any one time. Likewise, genetic hybrids displaying nucleolar dominance transcribe rRNA genes inherited from one parent but silence the other paraental set.We show that rRNA gene dosage control and nucleolar dominance utilize a common mechanism
Autores principais:Silva, Manuela
Outros Autores:Viegas, Wanda; Lawrence, Richard J.; Early, Keith; Pontes, Olga; Chen, Z.; Neves, Nuno; Pikaard, Craig S.
Assunto:eukaryotes rRNA nucleolar dominance
Ano:2004
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
Descrição
Resumo:Eukaryotes regulate the effective dosage of their ribosomal RNA (rRNA) genes, expressing fewer than half of the genes at any one time. Likewise, genetic hybrids displaying nucleolar dominance transcribe rRNA genes inherited from one parent but silence the other paraental set.We show that rRNA gene dosage control and nucleolar dominance utilize a common mechanism