Publicação
The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons
| Resumo: | Neurotoxicity associated with increased glutamate release results in cell death through both necrotic and apoptotic processes. In addition, tauroursodeoxycholic acid ( TUDCA), an endogenous bile acid, is a strong modulator of apoptosis in several cell typ |
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| Autores principais: | Castro, RE |
| Outros Autores: | Sola, S; Ramalho, RM; Steer, CJ; Rodrigues, CMP |
| Assunto: | Pharmacology & Pharmacy |
| Ano: | 2004 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso a metadados |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Neurotoxicity associated with increased glutamate release results in cell death through both necrotic and apoptotic processes. In addition, tauroursodeoxycholic acid ( TUDCA), an endogenous bile acid, is a strong modulator of apoptosis in several cell typ |
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