Publicação
Valproate induces in vitro accumulation of long-chain fatty acylcarnitines
| Resumo: | To elucidate the interference mechanisms of valproate (VPA) with mitochondrial fatty acid beta -oxidation (FAO), the profile of acylcarnitine formation was studied in vitro. Human fibroblasts were incubated with 0.2 mmol/L [U-C-13]palmitate, 0.4 mmol/L L- |
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| Autores principais: | Silva, MFB |
| Outros Autores: | Jakobs, C; Duran, M; de Almeida, IT; Wanders, RJA |
| Assunto: | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| Ano: | 2001 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso a metadados |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | To elucidate the interference mechanisms of valproate (VPA) with mitochondrial fatty acid beta -oxidation (FAO), the profile of acylcarnitine formation was studied in vitro. Human fibroblasts were incubated with 0.2 mmol/L [U-C-13]palmitate, 0.4 mmol/L L- |
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