Publicação
Valproate induces in vitro accumulation of long-chain fatty acylcarnitines
| Resumo: | To elucidate the interference mechanisms of valproate (VPA) with mitochondrial fatty acid beta -oxidation (FAO), the profile of acylcarnitine formation was studied in vitro. Human fibroblasts were incubated with 0.2 mmol/L [U-C-13]palmitate, 0.4 mmol/L L- |
|---|---|
| Autores principais: | Silva, MFB |
| Outros Autores: | Jakobs, C; Duran, M; de Almeida, IT; Wanders, RJA |
| Assunto: | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| Ano: | 2001 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso a metadados |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| _version_ | 1866808913389682688 |
|---|---|
| author | Silva, MFB |
| author2 | Jakobs, C Duran, M de Almeida, IT Wanders, RJA |
| author2_role | author author author author |
| author_facet | Silva, MFB Jakobs, C Duran, M de Almeida, IT Wanders, RJA |
| author_role | author |
| contributor_name_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Silva, MFB\"},{\"Person.name\":\"Jakobs, C\"},{\"Person.name\":\"Duran, M\"},{\"Person.name\":\"de Almeida, IT\"},{\"Person.name\":\"Wanders, RJA\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| datacite.creators.creator.creatorName.fl_str_mv | Silva, MFB Jakobs, C Duran, M de Almeida, IT Wanders, RJA |
| datacite.date.Accepted.fl_str_mv | 2001-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2015-12-30T10:17:57Z |
| datacite.date.embargoed.fl_str_mv | 2015-12-30T10:17:57Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_14cb |
| datacite.subjects.subject.fl_str_mv | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| datacite.titles.title.fl_str_mv | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| dc.contributor.none.fl_str_mv | Repositório Científico de Acesso Aberto da ULisboa |
| dc.creator.none.fl_str_mv | Silva, MFB Jakobs, C Duran, M de Almeida, IT Wanders, RJA |
| dc.date.Accepted.fl_str_mv | 2001-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2015-12-30T10:17:57Z |
| dc.date.embargoed.fl_str_mv | 2015-12-30T10:17:57Z |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10451/21330 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | ACADEMIC PRESS INC |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_14cb |
| dc.subject.none.fl_str_mv | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| dc.title.fl_str_mv | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | To elucidate the interference mechanisms of valproate (VPA) with mitochondrial fatty acid beta -oxidation (FAO), the profile of acylcarnitine formation was studied in vitro. Human fibroblasts were incubated with 0.2 mmol/L [U-C-13]palmitate, 0.4 mmol/L L- |
| dirty | 0 |
| eu_rights_str_mv | metadataOnlyAccess |
| format | article |
| id | ul_8a7768f044bb62348e52dfaa8dffc704 |
| identifier.url.fl_str_mv | http://hdl.handle.net/10451/21330 |
| instacron_str | ul |
| institution | Universidade de Lisboa |
| instname_str | Universidade de Lisboa |
| language | eng |
| network_acronym_str | ul |
| network_name_str | Repositório da Universidade de Lisboa |
| oai_identifier_str | oai:repositorio.ulisboa.pt:10451/21330 |
| organization_str_mv | urn:organizationAcronym:ul |
| person_str_mv | Silva, MFB Jakobs, C Duran, M de Almeida, IT Wanders, RJA |
| publishDate | 2001 |
| publisher.none.fl_str_mv | ACADEMIC PRESS INC |
| reponame_str | Repositório da Universidade de Lisboa |
| repository_id_str | urn:repositoryAcronym:ul |
| service_str_mv | urn:repositoryAcronym:ul |
| spelling | engACADEMIC PRESS INCTo elucidate the interference mechanisms of valproate (VPA) with mitochondrial fatty acid beta -oxidation (FAO), the profile of acylcarnitine formation was studied in vitro. Human fibroblasts were incubated with 0.2 mmol/L [U-C-13]palmitate, 0.4 mmol/L L-Valproate induces in vitro accumulation of long-chain fatty acylcarnitinesSilva, MFBJakobs, CDuran, Mde Almeida, ITWanders, RJAHostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptISSNIsPartOf1096-71922015-12-30T10:17:57Z20012001-01-01T00:00:00ZHandlehttp://hdl.handle.net/10451/21330http://purl.org/coar/access_right/c_14cbmetadata only accessBiochemistry & Molecular BiologyGenetics & HeredityMedicine, Research & Experimentalliteraturehttp://purl.org/coar/resource_type/c_6501journal articleMOLECULAR GENETICS AND METABOLISMVol. 73358361 |
| spellingShingle | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines Silva, MFB Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| status | SINGLETON |
| subject.fl_str_mv | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| title | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| title_full | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| title_fullStr | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| title_full_unstemmed | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| title_short | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| title_sort | Valproate induces in vitro accumulation of long-chain fatty acylcarnitines |
| topic | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| topic_facet | Biochemistry & Molecular Biology Genetics & Heredity Medicine, Research & Experimental |
| url | http://hdl.handle.net/10451/21330 |
| visible | 1 |