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Structural and spectral assignment of three forskolin-like diterpenoids isolated from Plectranthus ornatus

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Detalhes bibliográficos
Resumo:Three labdane diterpenoids were isolated from an acetone extract of Plectranthus ornatus. Their structures, closely related to that of forskolin, were determined by NMR studies. Unambiguous and complete assignments of the H-1 and C-13 NMR chemical shifts for these substances are presented. The assignments are based on 2D shift-correlated [H-1,H-1-COSY,H-1,C-13-gHSQC-(1)J (C,H), H-1, C-13-gHMBC-(n)J (C,H) (n = 2 and 3)] and NOE experiments. Copyright (c) 2005 John Wiley & Sons, Ltd.
Autores principais:Rijo, P
Outros Autores:Simoes, MF; Rodriguez, B
Assunto:Chemistry, Multidisciplinary Chemistry, Physical Spectroscopy
Ano:2005
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso a metadados
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
Descrição
Resumo:Three labdane diterpenoids were isolated from an acetone extract of Plectranthus ornatus. Their structures, closely related to that of forskolin, were determined by NMR studies. Unambiguous and complete assignments of the H-1 and C-13 NMR chemical shifts for these substances are presented. The assignments are based on 2D shift-correlated [H-1,H-1-COSY,H-1,C-13-gHSQC-(1)J (C,H), H-1, C-13-gHMBC-(n)J (C,H) (n = 2 and 3)] and NOE experiments. Copyright (c) 2005 John Wiley & Sons, Ltd.