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Complete beta-oxidation of valproate

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Detalhes bibliográficos
Resumo:The beta-oxidation of valproic acid (VPA; 2-n-propylpentanoic acid) was investigated in vitro in intact rat liver mitochondria incubated with H-3-labelled VPA. The metabolism of [4,5-H-3(2)]VPA and [2-H-3]VPA was studied by analysing the different acyl-Co
Autores principais:Silva, MFB
Outros Autores:Ruiter, JPN; Overmars, H; Bootsma, AH; van Gennip, AH; Jakobs, C; Duran, M; de Alemida, IT; Wanders, RJA
Assunto:Biochemistry & Molecular Biology
Ano:2002
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso a metadados
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
Descrição
Resumo:The beta-oxidation of valproic acid (VPA; 2-n-propylpentanoic acid) was investigated in vitro in intact rat liver mitochondria incubated with H-3-labelled VPA. The metabolism of [4,5-H-3(2)]VPA and [2-H-3]VPA was studied by analysing the different acyl-Co