Publicação
Impact of excess body weight on skin hydration and biomechanics
| Resumo: | The WHO regards obesity as an epidemic, affecting more than one third of adults in the United States. Obesity is a key factor for several comorbidities, and naturally, the skin is a major organ involved. This study aims to add knowledge to the characterization of skin functional changes related with excessive body weight. A sample of 30 healthy female volunteers, 29–46 (36 ± 4) years old, was selected and divided into three groups dependent on their respective body mass index (BMI) – Group I with BMI between 19.9 and 24.9 kg/m2, Group II with BMI between 25 and 29.9 kg/m2, and Group III with BMI between 30 and 39.9 kg/m2. Skin physiology was assessed by transepidermal water loss (TEWL), epidermal hydration (barrier function), and biomechanical descriptors (“envelope” function). Results have shown that excessive body weight compromises both the barrier function and the biomechanical behavior, but the magnitude depends on the severity of obesity and the anatomical area considered. Nevertheless, further studies are still needed to better understand this pathophysiology’s impact on human skin. |
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| Autores principais: | Tavares, Liliana |
| Outros Autores: | Palma, Lídia; Santos, Osvaldo; Roberto, Maria Angélica; Bujan, Maria Julia; Rodrigues, Luís Monteiro |
| Assunto: | Overweight BMI Skin physiology Epidermal water Skin biomechanics |
| Ano: | 2015 |
| País: | Portugal |
| Tipo de documento: | capítulo de livro |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | The WHO regards obesity as an epidemic, affecting more than one third of adults in the United States. Obesity is a key factor for several comorbidities, and naturally, the skin is a major organ involved. This study aims to add knowledge to the characterization of skin functional changes related with excessive body weight. A sample of 30 healthy female volunteers, 29–46 (36 ± 4) years old, was selected and divided into three groups dependent on their respective body mass index (BMI) – Group I with BMI between 19.9 and 24.9 kg/m2, Group II with BMI between 25 and 29.9 kg/m2, and Group III with BMI between 30 and 39.9 kg/m2. Skin physiology was assessed by transepidermal water loss (TEWL), epidermal hydration (barrier function), and biomechanical descriptors (“envelope” function). Results have shown that excessive body weight compromises both the barrier function and the biomechanical behavior, but the magnitude depends on the severity of obesity and the anatomical area considered. Nevertheless, further studies are still needed to better understand this pathophysiology’s impact on human skin. |
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