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The diagnostic significance of periportal hepatic necrosis and inflammation

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Detalhes bibliográficos
Resumo:In this review the several types of cell damage and cell death which may be found in liver biopsy specimens are defined. We describe the different processes which occur at the portal/parenchymal or septal/parenchymal interface, viz. periportal spillover, periportal hepatitis, classic or lymphocytic piecemeal necrosis and biliary piecemeal necrosis. The diagnostic implications of these lesions in relation to the clinicopathological diagnosis and prognosis in various liver diseases are discussed.
Autores principais:Baptista, A.
Outros Autores:Bianchi, L.; De Groote, J.; Desmet, V. J.; Ishak, K. G.; Korb, G.; MacSween, R. N.; Popper, H.; Poulsen, H.; Scheuer, P. J.
Assunto:Acute and chronic liver disease Liver cell necrosis Periportal spillover Periportal hepatitis Piecemeal necrosis
Ano:1988
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Universidade de Lisboa
Idioma:inglês
Origem:Repositório da Universidade de Lisboa
Descrição
Resumo:In this review the several types of cell damage and cell death which may be found in liver biopsy specimens are defined. We describe the different processes which occur at the portal/parenchymal or septal/parenchymal interface, viz. periportal spillover, periportal hepatitis, classic or lymphocytic piecemeal necrosis and biliary piecemeal necrosis. The diagnostic implications of these lesions in relation to the clinicopathological diagnosis and prognosis in various liver diseases are discussed.