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Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática

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Resumo:Inverted Papilloma is a benign tumour that arises in the nasal cavity and paranasal sinuses, and that despite being rare, shows a challenging biologic behaviour due to: its local aggressiveness, a high recurrence rate, and its association with a malignant transformation. This study was motivated by the rarity of the disease and by its behaviour and it aims at reviewing the existing literature on the subject. Although the disease's etiology is not entirely known, it is thought that Human Papilloma Virus (HPV) is involved, despite the fact that the molecular basis of this disease have not been clarified yet. The diagnosis is anatomopathological and imaging-based, and CT scan, MRI and nasal endoscopy may be used. This review includes the definition of Inverted Papilloma, a description of its historic data, epidemiology, histopathology and etiology. Inverted Papilloma's biologic behaviour, molecular basis and clinical presentation are also approached. Finally, diagnosis, staging and treatment are also discussed. The treatment of this type of lesion still remains a clinical challenge to otolaryngologists. However, there is certainty about using surgery as a first choice and on the fact that a long-term follow-up is necessary for this kind of patients.
Autores principais:Tomás, Ana Rita Vieira Sousa
Assunto:Papiloma invertido Fossas nasais Seios perinasais Vírus do papiloma humano (VPH)
Ano:2014
País:Portugal
Tipo de documento:dissertação de mestrado
Tipo de acesso:acesso restrito
Instituição associada:Universidade de Lisboa
Idioma:português
Origem:Repositório da Universidade de Lisboa
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author Tomás, Ana Rita Vieira Sousa
author_facet Tomás, Ana Rita Vieira Sousa
Tomás, Ana Rita Vieira Sousa
author_role author
contributor_name_str_mv Pereira, Miguel
Marques, Marta Canas
Repositório Científico de Acesso Aberto da ULisboa
country_str PT
creators_json_str [{\"Person.name\":\"Tomás, Ana Rita Vieira Sousa\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Pereira, Miguel
Marques, Marta Canas
Repositório Científico de Acesso Aberto da ULisboa
datacite.creators.creator.creatorName.fl_str_mv Tomás, Ana Rita Vieira Sousa
datacite.date.Accepted.fl_str_mv 2014-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2016-05-31T11:27:36Z
datacite.date.embargoed.fl_str_mv 2016-05-31T11:27:36Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
datacite.titles.title.fl_str_mv Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
dc.contributor.none.fl_str_mv Pereira, Miguel
Marques, Marta Canas
Repositório Científico de Acesso Aberto da ULisboa
dc.creator.none.fl_str_mv Tomás, Ana Rita Vieira Sousa
dc.date.Accepted.fl_str_mv 2014-01-01T00:00:00Z
dc.date.available.fl_str_mv 2016-05-31T11:27:36Z
dc.date.embargoed.fl_str_mv 2016-05-31T11:27:36Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10451/23863
dc.language.none.fl_str_mv por
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
dc.title.fl_str_mv Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_bdcc
description Inverted Papilloma is a benign tumour that arises in the nasal cavity and paranasal sinuses, and that despite being rare, shows a challenging biologic behaviour due to: its local aggressiveness, a high recurrence rate, and its association with a malignant transformation. This study was motivated by the rarity of the disease and by its behaviour and it aims at reviewing the existing literature on the subject. Although the disease's etiology is not entirely known, it is thought that Human Papilloma Virus (HPV) is involved, despite the fact that the molecular basis of this disease have not been clarified yet. The diagnosis is anatomopathological and imaging-based, and CT scan, MRI and nasal endoscopy may be used. This review includes the definition of Inverted Papilloma, a description of its historic data, epidemiology, histopathology and etiology. Inverted Papilloma's biologic behaviour, molecular basis and clinical presentation are also approached. Finally, diagnosis, staging and treatment are also discussed. The treatment of this type of lesion still remains a clinical challenge to otolaryngologists. However, there is certainty about using surgery as a first choice and on the fact that a long-term follow-up is necessary for this kind of patients.
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instname_str Universidade de Lisboa
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oai_identifier_str oai:repositorio.ulisboa.pt:10451/23863
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person_str_mv Tomás, Ana Rita Vieira Sousa
publishDate 2014
reponame_str Repositório da Universidade de Lisboa
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spelling porpt_PTInverted Papilloma is a benign tumour that arises in the nasal cavity and paranasal sinuses, and that despite being rare, shows a challenging biologic behaviour due to: its local aggressiveness, a high recurrence rate, and its association with a malignant transformation. This study was motivated by the rarity of the disease and by its behaviour and it aims at reviewing the existing literature on the subject. Although the disease's etiology is not entirely known, it is thought that Human Papilloma Virus (HPV) is involved, despite the fact that the molecular basis of this disease have not been clarified yet. The diagnosis is anatomopathological and imaging-based, and CT scan, MRI and nasal endoscopy may be used. This review includes the definition of Inverted Papilloma, a description of its historic data, epidemiology, histopathology and etiology. Inverted Papilloma's biologic behaviour, molecular basis and clinical presentation are also approached. Finally, diagnosis, staging and treatment are also discussed. The treatment of this type of lesion still remains a clinical challenge to otolaryngologists. However, there is certainty about using surgery as a first choice and on the fact that a long-term follow-up is necessary for this kind of patients.application/pdfpt_PTPapiloma invertido das fossas nasais e seios perinasais : revisão sistemáticaTomás, Ana Rita Vieira SousaPereira, MiguelMarques, Marta CanasHostingInstitutionOrganizationalRepositório Científico de Acesso Aberto da ULisboae-mailmailto:repositorio@reitoria.ulisboa.ptrepositorio@reitoria.ulisboa.ptURNurn:tid:2010559612016-05-31T11:27:36Z20142014-01-01T00:00:00ZHandlehttp://hdl.handle.net/10451/23863http://purl.org/coar/access_right/c_16ecrestricted accessPapiloma invertidoFossas nasaisSeios perinasaisVírus do papiloma humano (VPH)920858 bytesliteraturehttp://purl.org/coar/resource_type/c_bdccmaster thesishttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://repositorio.ulisboa.pt/bitstreams/ae4651c5-d70d-4dbd-a88a-bb3393ad1bd2/download
spellingShingle Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
Tomás, Ana Rita Vieira Sousa
Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
Tomás, Ana Rita Vieira Sousa
Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
status SINGLETON
subject.fl_str_mv Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
title Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
title_full Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
title_fullStr Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
title_full_unstemmed Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
title_short Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
title_sort Papiloma invertido das fossas nasais e seios perinasais : revisão sistemática
topic Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
topic_facet Papiloma invertido
Fossas nasais
Seios perinasais
Vírus do papiloma humano (VPH)
url http://hdl.handle.net/10451/23863
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