Publicação
Genetic characterisation of the ethambutol resistance-determining region in Mycobacterium tuberculosis
| Resumo: | Ethambutol (EMB) is a first-line antitubercular drug that inhibits arabinogalactan and lipoarabinomannan biosynthesis. Resistance to EMB has traditionally been associated with embB mutations, especially in the Met306 codon. In this study, the region encom. - Fundacao Calouste Gulbenkian, Lisbon, Portugal [FCG 001013]. - Funding: This work was supported by Fundacao Calouste Gulbenkian, Lisbon, Portugal (grant FCG 001013). |
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| Autores principais: | Perdigao, Joao |
| Outros Autores: | Macedo, Rita; Ribeiro, Ana; Brum, Laura; Portugal, Isabel |
| Assunto: | Infectious Diseases Microbiology Pharmacology & Pharmacy |
| Ano: | 2009 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso a metadados |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Ethambutol (EMB) is a first-line antitubercular drug that inhibits arabinogalactan and lipoarabinomannan biosynthesis. Resistance to EMB has traditionally been associated with embB mutations, especially in the Met306 codon. In this study, the region encom. - Fundacao Calouste Gulbenkian, Lisbon, Portugal [FCG 001013]. - Funding: This work was supported by Fundacao Calouste Gulbenkian, Lisbon, Portugal (grant FCG 001013). |
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