Publicação
Hemangiomatose neonatal difusa : caso clínico
| Resumo: | Infantile hemangiomas are the most common benign vascular tumors in children. The majority have a benign course with spontaneous regression of the lesions, without the need for pharmacological or surgical treatment. The presence of at least five localized cutaneous hemangiomas is called neonatal hemangiomatosis, which presents two forms, benign and diffuse. Diffuse neonatal hemangiomatosis is a rare disorder characterized by multiple cutaneous and visceral hemangiomas and high mortality in the first months of life. Therapy with propranolol is now considered first-line in complicated hemangiomas. There are several studies proving its efficacy in all phases of the natural history of the hemangioma with few reported side effects. We describe the clinical case of an infant with two months of age with diffuse neonatal hemangiomatosis with involvement of the liver, spleen, lung and spinal canal with cerebral arteriovenous malformation, association infrequently described in the literature. The introduction of therapy with propranolol proved to be effective, and the child, now with eleven months of age, is clinically well and with imagiological regression of the lesions. |
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| Autores principais: | Pereira, Laura Xavier de Sá Pais |
| Assunto: | Hemangiomas infantis Propranolol Pediatria |
| Ano: | 2014 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso restrito |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | português |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Infantile hemangiomas are the most common benign vascular tumors in children. The majority have a benign course with spontaneous regression of the lesions, without the need for pharmacological or surgical treatment. The presence of at least five localized cutaneous hemangiomas is called neonatal hemangiomatosis, which presents two forms, benign and diffuse. Diffuse neonatal hemangiomatosis is a rare disorder characterized by multiple cutaneous and visceral hemangiomas and high mortality in the first months of life. Therapy with propranolol is now considered first-line in complicated hemangiomas. There are several studies proving its efficacy in all phases of the natural history of the hemangioma with few reported side effects. We describe the clinical case of an infant with two months of age with diffuse neonatal hemangiomatosis with involvement of the liver, spleen, lung and spinal canal with cerebral arteriovenous malformation, association infrequently described in the literature. The introduction of therapy with propranolol proved to be effective, and the child, now with eleven months of age, is clinically well and with imagiological regression of the lesions. |
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