Publicação
Characterizing knee biomechanics during motion and loading using a specialized MRI-safe device: A kinematic and EMG focused analysis to validate CINE-MRI techniques for the knee joint
| Resumo: | This thesis investigated the potential of using CINE-MRI for dynamic knee joint imaging, and assessed its reliability challenges using a dedicated knee motion/loading device. Motion consistency across movement cycles, crucial for accurate image averaging and high-resolution imaging outcomes, was assessed through analytical and statistical tests of knee kinematic and electromyography data, resulting in practical recommendations to enhance knee motion reliability and, ultimately, CINE-MRI outcomes. Reliability analyses using intraclass correlation coefficients (ICCs) and standard error of measurement (SEM) indicated higher knee motion repeatability in the second trial of a given condition, suggesting the benefit of a practice trial before actual data collection for improved repeatability. Knee angle range of motion measurements demonstrated good to excellent relative and absolute reliabilities (ICC 0.85-0.94; SEM 0.63º-0.96º), while knee extension and flexion velocities exhibited lower relative reliability (ICCs 0.56-0.70 and 0.60-0.82; SEMs 0.44º/sec-0.53º/sec and 0.26º/sec-0.54º/sec, respectively). Furthermore, quadriceps muscle activation displayed good relative reliability (ICCsrectus femoris 0.81-0.88; vastus lateralis 0.84-0.88; vastus medialis 0.78-0.84) but poor absolute reliability (SEMs rectus femoris 0.11-0.16; vastus lateralis 0.10-0.13; vastus medialis 0.10-0.14), which may have implications concerning underlying assumptions of tissue deformation uniformity required for valid image averaging. Hamstrings-to-quadriceps activation and muscle fatigue effects were examined. Minimal hamstring co-activation and a decrease in mean and median frequency were confirmed during knee motion/loading trials. Repeated measures ANOVAs revealed that the first cycle of each trial differed significantly from subsequent cycles across most parameters, suggesting its exclusion during data averaging. Combined with fatigue analysis, electromyography amplitude increased significantly from the first to the last cycle, suggesting fatigue development. This study had limitations, including a small sample size, potential outliers’ impact, and betweenparticipant differences in outcomes. Nevertheless, the research achieved its objectives, not only of evaluating the reliability of CINE-MRI protocols but also providing key recommendations for enhancement of CINE-MRI application. |
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| Autores principais: | Oliveira, João Filipe Garcia |
| Assunto: | Ressonância magnética dinâmica (RM) CINE-RM movimento do joelho eletromiografia de repetibilidade de movimento fadiga muscular Teses de mestrado - 2024 |
| Ano: | 2024 |
| País: | Portugal |
| Tipo de documento: | dissertação de mestrado |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | This thesis investigated the potential of using CINE-MRI for dynamic knee joint imaging, and assessed its reliability challenges using a dedicated knee motion/loading device. Motion consistency across movement cycles, crucial for accurate image averaging and high-resolution imaging outcomes, was assessed through analytical and statistical tests of knee kinematic and electromyography data, resulting in practical recommendations to enhance knee motion reliability and, ultimately, CINE-MRI outcomes. Reliability analyses using intraclass correlation coefficients (ICCs) and standard error of measurement (SEM) indicated higher knee motion repeatability in the second trial of a given condition, suggesting the benefit of a practice trial before actual data collection for improved repeatability. Knee angle range of motion measurements demonstrated good to excellent relative and absolute reliabilities (ICC 0.85-0.94; SEM 0.63º-0.96º), while knee extension and flexion velocities exhibited lower relative reliability (ICCs 0.56-0.70 and 0.60-0.82; SEMs 0.44º/sec-0.53º/sec and 0.26º/sec-0.54º/sec, respectively). Furthermore, quadriceps muscle activation displayed good relative reliability (ICCsrectus femoris 0.81-0.88; vastus lateralis 0.84-0.88; vastus medialis 0.78-0.84) but poor absolute reliability (SEMs rectus femoris 0.11-0.16; vastus lateralis 0.10-0.13; vastus medialis 0.10-0.14), which may have implications concerning underlying assumptions of tissue deformation uniformity required for valid image averaging. Hamstrings-to-quadriceps activation and muscle fatigue effects were examined. Minimal hamstring co-activation and a decrease in mean and median frequency were confirmed during knee motion/loading trials. Repeated measures ANOVAs revealed that the first cycle of each trial differed significantly from subsequent cycles across most parameters, suggesting its exclusion during data averaging. Combined with fatigue analysis, electromyography amplitude increased significantly from the first to the last cycle, suggesting fatigue development. This study had limitations, including a small sample size, potential outliers’ impact, and betweenparticipant differences in outcomes. Nevertheless, the research achieved its objectives, not only of evaluating the reliability of CINE-MRI protocols but also providing key recommendations for enhancement of CINE-MRI application. |
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