Publication
Comparative study of the healing process of disbudding wounds using Bepanthene® or Cyclospray®
| Summary: | Comparative study of the healing process of disbudding wounds using Bepanthene® or Cyclospray® - The process of disbudding/dehorning is common in most dairy farms, benefiting the handling, transportation and welfare of the animals. The most prevalent method is cautery disbudding, responsible for destroying the horn bud and horn generating tissue. After the procedure, usually, the wounds are treated with an antibiotic based spray. Nowadays, antibiotic resistances are associated with high rates of morbidity and mortality, both in human and veterinary medicine, highlighting the need to invest in the monitoring of antibiotic use, new policies and the development of alternative treatment, in favor of One Health. The goal of this prospective study is to minimize the use of antibiotics in production animals, resorting to alternative treatments of disbudding wounds. The Bepanthene® (Dexpanthenol) is a plausible option, since it is wildly used in human medicine for the treatment of skin irritations and burns. The comparison of the healing process of disbudding wounds, treated with Bepanthene® or Cyclopsray® (Chlortetracycline), was achieved through the presentation of images of the lesions to a panel of blind evaluators, constituted by seven veterinarians, five veterinary medicine students, and five human medical field nurses. In order to classify the lesions, the panel applied an adapted format of a verified healing scale, Bates-Jensen Wound Assessment Tool, incorporating seven parameters of evaluation, culminating in a total value, used in the statistical analyses. In the veterinarians’ evaluation, there was a statistically significant difference (P value <0.05), between the two products, for the parameter “Edges”, indicating that the Bepanthene® is superior to the Cyclopsray® in this specific parameter of healing. The assessment of the veterinary students showed a statistically significant difference, between the products, for the parameters “Exudate Type” and “Exudate Amount”, showing the superiority of the Bepanthene’s® action in the mentioned parameters. The evaluation presented by the nurses from the human medical field showed no statistically significant difference between the two products for any of the parameters. Lastly, the joint assessment, considering all of the evaluations, demonstrated statistically significant differences, between the two products, for the parameters “Edges” and “Necrotic Tissue Type”, in favor of the Bepanthene®. These findings lead us to conclude that the Bepanthene® presented a better healing index, compared to the Cyclopsray®, allowing it to be considered as a safe alternative to the antibiotic based spray. |
|---|---|
| Main Authors: | Martins, Gabriela Dias |
| Subject: | Bepanthene® Cyclospray® Disbudding Dehorning Resistance Antibiotics Bepanthene® Cyclospray® Descorna Resistência Antibióticos |
| Year: | 2022 |
| Country: | Portugal |
| Document type: | master thesis |
| Access type: | open access |
| Associated institution: | Universidade de Lisboa |
| Language: | English |
| Origin: | Repositório da Universidade de Lisboa |
| Summary: | Comparative study of the healing process of disbudding wounds using Bepanthene® or Cyclospray® - The process of disbudding/dehorning is common in most dairy farms, benefiting the handling, transportation and welfare of the animals. The most prevalent method is cautery disbudding, responsible for destroying the horn bud and horn generating tissue. After the procedure, usually, the wounds are treated with an antibiotic based spray. Nowadays, antibiotic resistances are associated with high rates of morbidity and mortality, both in human and veterinary medicine, highlighting the need to invest in the monitoring of antibiotic use, new policies and the development of alternative treatment, in favor of One Health. The goal of this prospective study is to minimize the use of antibiotics in production animals, resorting to alternative treatments of disbudding wounds. The Bepanthene® (Dexpanthenol) is a plausible option, since it is wildly used in human medicine for the treatment of skin irritations and burns. The comparison of the healing process of disbudding wounds, treated with Bepanthene® or Cyclopsray® (Chlortetracycline), was achieved through the presentation of images of the lesions to a panel of blind evaluators, constituted by seven veterinarians, five veterinary medicine students, and five human medical field nurses. In order to classify the lesions, the panel applied an adapted format of a verified healing scale, Bates-Jensen Wound Assessment Tool, incorporating seven parameters of evaluation, culminating in a total value, used in the statistical analyses. In the veterinarians’ evaluation, there was a statistically significant difference (P value <0.05), between the two products, for the parameter “Edges”, indicating that the Bepanthene® is superior to the Cyclopsray® in this specific parameter of healing. The assessment of the veterinary students showed a statistically significant difference, between the products, for the parameters “Exudate Type” and “Exudate Amount”, showing the superiority of the Bepanthene’s® action in the mentioned parameters. The evaluation presented by the nurses from the human medical field showed no statistically significant difference between the two products for any of the parameters. Lastly, the joint assessment, considering all of the evaluations, demonstrated statistically significant differences, between the two products, for the parameters “Edges” and “Necrotic Tissue Type”, in favor of the Bepanthene®. These findings lead us to conclude that the Bepanthene® presented a better healing index, compared to the Cyclopsray®, allowing it to be considered as a safe alternative to the antibiotic based spray. |
|---|