Publicação
Arrhythmogenic right ventricular cardiomyopathy in boxer dogs: retrospective study (6 cases)
| Resumo: | Arrhythmogenic right ventricle cardiomyopathy (ARVC) is recognized in Boxers, cats and humans, is characterized clinically by ventricular tachyarrhythmias and histopathologically by fibrofatty replacement, mostly of the right ventricle. Affected dogs may have syncope, exercise intolerance or heart failure associated signs. ARVC is an inherited adult onset disorder that can lead to sudden death which can also be the first and single clinical sign. Ventricular premature complexes (VPC’s) with left bundle branch block morphology on the electrocardiogram (ECG) are typical for the disease. These VPCs can occur singly, in pairs, triplets or runs of ventricular tachycardia (VT). Routine ECG can be insensitive for the detection of ventricular arrhythmias when compared with a 24 hour Holter study. The antiarrhythmic drugs most commonly used are sotalol or mexiletine-atenolol association. A 24 hour Holter study should be repeated in order to evaluate the efficacy of treatment or detect a proarrhythmic effect. In this study, 4 out of 6 animals (66,6%) died suddenly, however owners refer an improvement in the animal’s quality of life once the treatment is initiated. The prognosis of this disease is guarded due to sudden death risk or heart failure development. |
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| Autores principais: | Bota, Doroteia Isabel Viegas Filipe |
| Assunto: | Boxer ARVC Ventricular tachyarrhythmias Syncope Sudden death Boxers CAVD Taquiarritmias ventriculares Síncope Morte súbita |
| Ano: | 2009 |
| País: | Portugal |
| Tipo de documento: | trabalho de fim de curso |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Lisboa |
| Idioma: | inglês |
| Origem: | Repositório da Universidade de Lisboa |
| Resumo: | Arrhythmogenic right ventricle cardiomyopathy (ARVC) is recognized in Boxers, cats and humans, is characterized clinically by ventricular tachyarrhythmias and histopathologically by fibrofatty replacement, mostly of the right ventricle. Affected dogs may have syncope, exercise intolerance or heart failure associated signs. ARVC is an inherited adult onset disorder that can lead to sudden death which can also be the first and single clinical sign. Ventricular premature complexes (VPC’s) with left bundle branch block morphology on the electrocardiogram (ECG) are typical for the disease. These VPCs can occur singly, in pairs, triplets or runs of ventricular tachycardia (VT). Routine ECG can be insensitive for the detection of ventricular arrhythmias when compared with a 24 hour Holter study. The antiarrhythmic drugs most commonly used are sotalol or mexiletine-atenolol association. A 24 hour Holter study should be repeated in order to evaluate the efficacy of treatment or detect a proarrhythmic effect. In this study, 4 out of 6 animals (66,6%) died suddenly, however owners refer an improvement in the animal’s quality of life once the treatment is initiated. The prognosis of this disease is guarded due to sudden death risk or heart failure development. |
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