Detalhes bibliográficos
| Resumo: | Background and aims: fecal microbiota transplantation (FMT) is effective for recurrent Clostridium difficile infection (CDI). Intestinal decolonization of carbapenamase-producing enterobacteriaceae (CPE) can prevent transmission and infection by these agents. The aim of this study was to assess CPE decolonization after FMT. Methods: this was a case-series study that consecutively included all CPE-carriers that underwent FMT between 2014 and 2019. The indications included refractory/recurrent CDI and CPE-decolonization. Results: out of 21 CPE-carriers, eight were excluded due to incomplete post-FMT testing. CPE decolonization was confirmed in 76.9 % (n = 10). The median decolonization time was 16-weeks (IQR-23) and ranged from two to 53 weeks. Conclusion: FMT may be used in the clinical practice for CPE-decolonization as an alternative to combined antibiotic regimens. |
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| Autores principais: | Silva, João Carlos |
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| Outros Autores: | Ponte, Ana; Mota, Margarida; Pinho, Rolando; Vieira, Nuno; Oliveira, Rosa; Mota-Carvalho, Nelson; Gomes, Ana Catarina; Afecto, Edgar; Carvalho, João |
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| Assunto: | Fecal microbiota transplantation Carbapenamase-producing enterobacteriaceae Multidrug-resistant infections Decolonization Intestinal carriage |
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| Ano: | 2020 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | acesso aberto |
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| Instituição associada: | Universidade Católica Portuguesa |
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| Idioma: | inglês |
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| Origem: | Veritati - Repositório Institucional da Universidade Católica Portuguesa |
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