Publicação
Encapsulation of rosmarinic acid into chitosan nanoparticles
| Resumo: | Introduction: The use of nanotechnology in medical sciences is a innovation that promises a new age of health. Among the different approaches explored so far, chitosan exhibits favourable and unique biological properties, such as biocompatibility, biodegradability, non-antigenic, non-toxicity and mucoadhesiveness . On the other hand, natural extracts have been incorporated in chitosan films, or macro/microparticles, becoming more effective as antimicrobial or improving the antioxidant protection. The combination of antioxidants and nanoparticles is seen as the key to success in the topical administration of therapeutic antioxidants . Phenolic compound like rosmarinic acid are potent natural antioxidant with a multitude of biological activities like anti-inflammatory, antimutagen, antibacterial and antiviral as well as high potential radical scavenging activity. |
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| Autores principais: | Silva, S. B. |
| Outros Autores: | Amorim, M.; Oliveira, A.; Ramos, O.; Pintado, M.; Ferreira, D.; Sarmento, B. |
| Ano: | 2011 |
| País: | Portugal |
| Tipo de documento: | documento de conferência |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade Católica Portuguesa |
| Idioma: | inglês |
| Origem: | Veritati - Repositório Institucional da Universidade Católica Portuguesa |
| Resumo: | Introduction: The use of nanotechnology in medical sciences is a innovation that promises a new age of health. Among the different approaches explored so far, chitosan exhibits favourable and unique biological properties, such as biocompatibility, biodegradability, non-antigenic, non-toxicity and mucoadhesiveness . On the other hand, natural extracts have been incorporated in chitosan films, or macro/microparticles, becoming more effective as antimicrobial or improving the antioxidant protection. The combination of antioxidants and nanoparticles is seen as the key to success in the topical administration of therapeutic antioxidants . Phenolic compound like rosmarinic acid are potent natural antioxidant with a multitude of biological activities like anti-inflammatory, antimutagen, antibacterial and antiviral as well as high potential radical scavenging activity. |
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