Author(s): Duarte, Tiago ; Caeiro, Fernando ; Góis, Mário ; Matos, António ; Viana, Lena ; Vieira, César ; Paulos, Jorge ; Paixão, Paulo ; Matos, Bruno ; Germano, Nuno ; Nolasco, Fernando
Date: 2021
Persistent ID: http://hdl.handle.net/10400.26/58614
Origin: Egas Moniz - Cooperativa de Ensino Superior, CRL
Subject(s): acute kidney injury; COVID-19; kidney biopsy
SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.
