Author(s):
Martins, AI ; Sargento-Freitas, J ; Jesus-Ribeiro, J ; Correia, I ; Cardoso, L ; Gomes, JP ; Gonçalves, M ; Costa, R ; Silva, F ; Galego, O ; Nunes, C ; Beato-Coelho, J ; Varela, R ; Machado, C ; Rodrigues, B ; Santo, GC ; Cunha, L
Date: 2018
Persistent ID: http://hdl.handle.net/10400.4/2262
Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
Subject(s): Pressão Arterial; Procedimentos Endovasculares; Acidente Vascular Cerebral; Resultado do Tratamento
Description
We performed a retrospective study with the aim of investigating the association between blood pressure (BP) variability in the first 24 h after ischemic stroke and functional outcome, regarding arterial recanalization status. A total of 674 patients diagnosed with acute stroke and treated with revascularization therapies were enrolled. Systolic and diastolic BP values of the first 24 h after stroke were collected and their variation quantified through standard deviation. Recanalization state was evaluated at 6 h and clinical outcome at 3 months was assessed by modified Rankin Scale. In multivariate analyses systolic BP variability in the first 24 h post-stroke showed an association with 3 months clinical outcome in the whole population and non-recanalyzed patients. In recanalyzed patients, BP variability did not show a significant association with functional outcome.